AKR ecotropic murine leukemia virus SL3-3 forms envelope gene recombinants in vivo
نویسندگان
چکیده
منابع مشابه
Murine Leukemia Virus Antigens in Akr
It is now well established that viruses of the murine leukemia virus (MuLV)' group are present ifi all m i ~ (1, 2) and that viral genetic sequences are present as chromosomal DNA (3-5). The expression of this genetic material, as virus particles or viral antigens, differs markedly between strains of mice, both with regard to the age at which the expression occurs (6-8) and the spectrum of biol...
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Extensive fusion occurs upon cocultivation of murine fibroblasts producing ecotropic murine leukemia viruses (MuLVs) with a large variety of murine cell lines in the presence of the polyene antibiotic amphotericin B, the active component of the antifungal agent Fungizone. The resulting polykaryocytes contain nuclei from both infected and uninfected cells, as evidenced by autoradiographic labeli...
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Recent studies have indicated that both the replication-defective spleen focus-forming virus (SFFV) in the Friend virus complex and the helper-independent mink cell focus-inducing (MCF) viruses derived from AKR-murine leukemia virus (MuLV) are env gene recombinants between ecotropic virus and xenotropic virus. In an attempt to isolate additional env gene recombinants between Friend murine leuke...
متن کاملMurine Leukemia Virus Group-specific Antigen Expression in AKR Mice1
The distribution of the group-specific murine leukemia virus antigen was studied by immunofluorescence and immunofluorescence absorption in embryo, neonatal, and postnatal normal AKR mice of various ages and in leukemic mice of this strain. MuLV-fs antigens were first detected during the first postnatal week in the liver, spleen, bone marrow, and serum, and during the second postnatal week in t...
متن کاملMurine leukemia virus group-specific antigen expression in AKR mice.
The distribution of the group-specific murine leukemia virus antigen was studied by immunofluorescence and immunofluorescence absorption in embryo, neonatal, and postnatal normal AKR mice of various ages and in leukemic mice of this strain. MuLV-fs antigens were first detected during the first postnatal week in the liver, spleen, bone marrow, and serum, and during the second postnatal week in t...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1986
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.59.1.23-30.1986